ABIDERS

PROJECT : Targeted delivery of antitumor drugs employing biodegradable carriers

ACRONIM : ABIDERS

Summary : The modern approach to the treatment of malignant diseases tends to focus on the individual patient, their general state of health and the targeted administration of drugs to the site of malignancy with as few side effects as possible associated with chemotherapy. The targeted administration of drugs requires that the protective envelope around the drug itself must be biodegradable but at the same time resistant to various external influences for the drug to reach the malignant cells. The envelope should be inert to changes in the pH value of the environment and sufficiently lipophilic to pass through the cell membrane of the malignant cells.

The aim of the project is to produce carriers made of biodegradable materials such as inulin and dextran, into which chemotherapeutic agents used in clinical practice are to be incorporated. Inulin and dextran are natural polymers used in the food industry and have no harmful effects on the body, which is the main reason for their selection as biodegradable carriers.

Lead partner:  Faculty of medicine Osijek, University of Josip Juraj Strossmayera in Osijek, Croatia

Project manager : Asistent professor Katarina Mišković Špoljarić, PhD

Project staff: prof. dr.sc. Ljubica Glavaš-Obrovac, PhD;  assistant professor Marijana Leventić, PhD; assistant professor Teuta Opačak-Bernardi, PhD; assistant professor Barbara Viljetić, PhD; Ivan Ćorić, assistant; Ivana Jelavić, bacc. med.lab.diag.

Project Partner : Institute of Food Technology in Novi Sad, , University of Novi Sad, Serbia

Project duration : 01.07.2024. – 31.12.2025.